The doctrine of nullification has a long and harshly contested legacy in the history of the United States—it has been invoked in defense of both just causes and frankly evil ones. But some argue that it is time to revisit the idea—to put an end to federal cannabis prohibition.

For a generation now, science has known of two cannabinoid receptors—specialized protein molecules that interact with the active compounds in the cannabis plant for the human body. These are CB1 and CB2, both discovered in the early '90s. Now there is growing awareness of a third such receptor that was identified in 2007. This receptor, GPR55, may be key to understanding a wide spectrum of therapeutic applications for cannabinoids—and especially the non-psychoactive cannabidiol, or CBD.
Emotional exchanges at City Council hearings in New York focused on the NYPD's "gang database," which critics say targets and stigmatizes even those who have long since cut ties to the city's "crews." The city has seen big militarized raids on housing projects as part of the crackdown on crews in recent years. But while heavy charges against suspected crew members made headlines at the time of the raids, little note was paid when some of those charges were downgraded to mere marijuana possession. Are claims of pot-dealing being used to place the city's Black and Latino youth on the database?
In the latest testament to fast-growing mainstream embrace of cannabis, Netflix this month debuts a competitive cooking show exclusively featuring dishes prepared with the herb. And not just for flavoring—under the show's rules, all recipes must actually get you high.
Something of a corporate scramble is underway to secure patents for the various curative properties of CBD, and associated products and procedures. Pharmaceutical firms see a windfall, but some activists raise concerns about the creeping privatization of a cannabinoid that should belong to the genetic and intellectual commons of the human race. How realistic are fears about the imminent arrival of "corporate cannabis"?
With US stock exchanges still almost entirely closed to cannabis businesses, the stateside industry is increasingly seeking access to the Canadian exchanges in order to secure investment. Taking over publicly traded Canadian firms through reverse mergers has emerged as the critical tactic in this endeavor.
In Humboldt County, famed as the heartland of Northern California's cannabis-producing Emerald Triangle, big police raids of cultivation sites—with thousands of plants eradicated—are continuing despite the Golden State's new legalization program. Many growers are choosing to remain underground, in spite of the risks to their property and freedom. And a big part of the reason why seems to lie in a confusing and contested county regulation regime.
Things are moving fast in the Empire State, with cannabis legalization proposals striding toward mainstream acceptance—spurred by a growing sense of injustice over the racial disparities in enforcement. In what could be a watershed moment, the state Democratic Party just adopted a resolution to embrace legalization. The party elite seem to be feeling the pressure from below in a gubernatorial election year.





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